Concept:Substitute the given value of n into the combination expression and evaluate using the factorial formula.Explanation:Given n=3, substitute into n2+1Cn+5:32+1C3+5=9+1C8=10C8Use the combination formula:10C8=8!(10−8)!10!=8!⋅2!10!Expand the factorials and cancel common terms:8!×2×110×9×8!=210×9=45Thus, the value of the expression is 45.Answer:B. 45