Concept:Express every term as a power of the same base, then equate the exponents.Explanation:Rewrite 16, 4x, and 81−x using base 2.16=24, 4x=22x, 81−x=23(1−x).The equation becomes:24⋅2x+1=22x⋅23(1−x).Add the exponents on both sides:2x+5=22x+3−3x.Simplify the exponent on the right:2x+5=23−x.Since the bases are equal, equate the exponents:x+5=3−x.Collect like terms:x+x=3−5.2x=−2.Divide both sides by 2:x=−1.Answer:x=−1, which is option D.