Concept:Use the binomial general term: in (a+b)n, the (r+1)th term is nCran−rbr.Explanation:Here, a=3x, b=−y, and n=6.The fourth term means r=3.So the fourth term is:T4=6C3(3x)6−3(−y)3=20×(3x)3×(−y)3=20×27x3×(−y3)=−540x3y3Answer:The fourth term is −540x3y3, which is Option A.