Concept:Sickle cell anaemia is an autosomal recessive genetic disorder.
Explanation:The disease allele is not sex-linked, so it affects males and females equally.
A carrier has the genotype
HbAHbS and usually does not show symptoms.
When two carriers marry, each parent can pass on the sickle cell allele.
The child may inherit
HbS from both parents, giving the genotype
HbSHbS, which causes sickle cell anaemia.
Thus, two carrier parents may indeed have a sickling child.
This makes the statement “two sickle cell carrier parents may have a sickling child” correct.
Answer:Two sickle cell carrier parents may have a sickling child.