Concept:Use the difference of two squares repeatedly: x2−y2=(x−y)(x+y).Explanation:Write 81a4 as (9a2)2 and 16b4 as (4b2)2.So 81a4−16b4=(9a2)2−(4b2)2.Factor the first difference of squares:=(9a2+4b2)(9a2−4b2).Now factor 9a2−4b2 again as a difference of squares:9a2−4b2=(3a−2b)(3a+2b).Thus the complete factorization is:(3a−2b)(3a+2b)(9a2+4b2).Answer:Option C: (3a−2b)(3a+2b)(9a2+4b2).