Concept:The probability that an integer picked is not in E2 is found by subtracting the probability of E2 from 1.Explanation:The universal set is U={1,2,3,…,20}, so the total number of outcomes is 20.E2={x:x is a multiple of 4} from U.Thus, E2={4,8,12,16,20}, which contains 5 elements.So, P(E2)=total elements in Unumber of elements in E2=205.Therefore, P(not in E2)=1−205=2020−5=2015.Simplifying, P(not in E2)=43.Answer:43(Option A).