JAMB Biology 2021 Paper

Concept:Blood transfusion depends on compatibility between donor red blood cell antigens and antibodies in the recipient's plasma.Explanation:Blood group $AB$ has both $A$ and $B$ antigens on its red blood cells.It does not have anti-$A$ or anti-$B$ antibodies in its plasma.Therefore, a person with blood group $AB$ can receive blood from all groups: $A$, $B$, $AB$, and $O$.This makes them a universal recipient.However, when $AB$ blood is given to a person with group $A$, group $B$, or group $O$, the recipient's antibodies attack the $A$ and $B$ antigens on the donated red blood cells.For this reason, $AB$ blood can be safely donated only to another $AB$ recipient.Group $O$ donors can donate to all groups, and groups $A$ and $B$ cannot donate to each other safely.Answer:The correct option is A: A person of blood group $AB$ can donate blood only to another person of blood group $AB$.